1-(tert-Butyl) 2-ethyl (2S,4S)-4-aminopyrrolidine-1,2-dicarboxylate - Names and Identifiers
| Name | 4-amino-1,2-Pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 2-ethyl ester, (2S,4S)
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| Synonyms | 1-(tert-Butyl) 2-ethyl (2S,4S)-4-aminopyrrolidine-1,2-dicarboxylate
4-amino-1,2-Pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 2-ethyl ester, (2S,4S)
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| CAS | 511242-54-9
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1-(tert-Butyl) 2-ethyl (2S,4S)-4-aminopyrrolidine-1,2-dicarboxylate - Physico-chemical Properties
1-(tert-Butyl) 2-ethyl (2S,4S)-4-aminopyrrolidine-1,2-dicarboxylate - Introduction
4-amino-1, acid 1-(1,1-dimethylethyl) 2-ethyl ester, (2S,4S) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 4-APDC is a white solid
-Melting point: about 105-110 ℃
-Molecular formula: C14H26N2O4
-Molecular weight: 294.37g/mol
Use:
- 4-APDC is a pharmaceutical intermediate used to synthesize other compounds or drugs
-It plays a role in stabilizing or improving the effect of drugs in the synthesis of drugs
Method:
The preparation method of-4-APDC is complicated and requires a series of chemical reactions and procedures:
1. First, the reaction generates 2-Ethoxypyrrolidine (2-Ethoxypyrrolidine)
2. React with N-substituted phthalimide (N-Substituted) to generate 2-ethoxy-4-pyrrolidone (2-Ethoxy-4-pyrrolidinone)
3. Further conversion of 2-ethoxy-4-pyrrolidone to 4-Pyrrolidinone methyl formamide
4. 4-pyrrolidine formamide reacts with DMF (dimethylformamide) and cuprous bromide to obtain the target product 4-APDC
Safety Information:
- 4-APDC has not been extensively studied and evaluated, so detailed toxicology and safety data are lacking
-When using and handling 4-APDC, follow the usual laboratory safety procedures, avoid contact with skin and eyes, and avoid inhalation or intake
-Comply with local regulations during handling and disposal to ensure a safe environment and the safety of health personnel
Last Update：2024-04-09 21:01:54